Med5382 Applied Pharmacogenomics And Molecular Assessment Answers
📄 1 Pages / 164 Words
Describe the Applied Pharmacogenomics and Molecular Medicine.
Answer:
Clinical features of ADR and HLA allele B*5701 include the following signs and symptoms that present as manifestations of the pathologic diseases. Drugs like Abacavir and Flucloxacillin have been indicated to present ADRS through HLA associations of this particular variant. Abacavir is a nucleoside reverse transcriptase inhibitor that is normally used in combination with other antiretroviral drugs for treatment of HIV might lead to hypersensitivity by exhibiting symptoms including fever, rash, malaise alongside constitutional symptoms, respiratory symptoms and gastrointestinal tract symptoms in conjunctional with organ involvement that are most prominent during the initial 2 to 6 weeks of treatment. Prolonged usage might aggravate the symptoms and pose severe threat to patient in case the patient is re-challenged following discontinuation. Further, for Flucloxacillin that is considered as a narrow spectrum anti-Staphylococcal semi-synthetic penicillin may induce hepatotoxicity. Common symptoms include cholestatic hepatitis that might manifest within 1-45 days post conduct of treatment (1).Buy Med5382 Applied Pharmacogenomics And Molecular Assessment Answers Online
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