BIOL121 The Harmful UV Radiation

Fill in the blank boxes to complete TWO rows of your choice in the following table, which summarises the name, location and function of a variety of cells throughout the body. The first line is completed as an example of the level of detail required.

Name the personal protective equipment that should be worn when handling someone else’s urine, and explain why those items are needed. 

Complete the table to compare how the following cells carry out the third line of defence:

• B-lymphocytes
• Cytotoxic T-lymphocytes

Some sections are completed for you to help guide your answers. 

The following paragraph refers to muscle contraction. Fill in each of the blanks to complete the paragraph using terms from the list provided.  More terms than necessary are provided, and terms may be used more 

The action potential spreads along the                                   , until it reaches a T-tubule. The action potential continues down the T-tubule, where it triggers the release of                            from the                                             . This exposes binding sites on                                 .                                heads bind to the exposed sites on                           to form cross-bridges.

Describe the role of osteoblasts and osteoclasts in the regulation of blood calcium ion concentration.  You must include the role of the relevant hormones for full marks. 

Describe how the hypothalamus controls the release of hormones from the:

1. anterior lobe of pituitary gland
2. posterior lobe of the pituitary gland

In your answer, give specific examples and clearly name any hormones involved.

Duchenne muscular dystrophy (DMD) is recessive sex-linked disorder, which causes muscle degeneration and premature death. A couple is pregnant with a boy and neither has DMD. The father’s family has no history of DMD, but the mother is unsure of her genetic family history as she was adopted. The mother decides to take advantage of some of the new genomic screening tests and learns information about a large number of her genes. She finds that she is a carrier of the DMD-affected allele. 

1. What is the mother’s genotype? Explain your reasoning.
2. What is the father’s genotype? Explain your reasoning. What is the likelihood of the male foetus having DMD? Use a Punnett square to explain your answer.

Describe the changes in volume and pressure inside the chest cavity during a normal, quiet exhalation. Explain why these changes are occurring, and the effect upon airflow.

Regarding quiet ventilation, which process is active — inhalation or exhalation? Briefly explain your answer.

The graph below displays the oxygen dissociation curve and factors that affect the release of oxygen from haemoglobin (Hb). Explain how these factors will affect the release of oxygen into the blood supply of a hard-working skeletal muscle.

Choose ONE of the blood types below and answer the following questions. Only the FIRST completed column will be marked

1. State the type of antigens found on the surface of those red blood cells, and the type of antibodies found in the plasma of a person with the blood type shown. Type your answer in the table below  (1 mark total)
2. Could a person with your chosen blood type safely receive type AB blood via transfusion?  Explain your answer below. 

Why is injury to the medulla oblongata usually fatal the following table summarising the effects of autonomic innervation on target tissues. You must include both the effect upon the target tissue and a consequence of this stimulation in your answer.The first row has been completed as an example. 

the paragraph below relates to this graph, which describes changes in membrane potential over time.

1. Fill in each of the blanks to complete the paragraph using terms from the list provided. More words than necessary are provided, and terms may be used more than once.
2. During                                   , the ­                      of the cell is 70 mV more negative than the                                           of the cell.  When a stimulus is applied, the membrane potential must reach                                                 in order for an Action Potential to be fired.  At the start of an Action Potential, Na⁺ channels open and Na⁺ ions                                the cell.  This phase is called                                   . 

The                                                         is the period of time in which the nerve membrane can start another action potential only if a much greater stimulus than usual is applied.

Referring to the graph above, at which numbered point do potassium gates begin to open

Antidiuretic hormone and aldosterone influence water and electrolyte balance of the body. The following table summarises the main characteristics of these hormones; your task is to fill in the empty cells in the table.

The following table describes the three elementary steps of urine formation. Complete the missing parts of the table. 

List two (2) differences between the external and internal urethral sphincters. The differences must relate to structure, function or innervation of these sphincters.

Explain how baroreceptors contribute to control blood pressure during a short period of widespread vasodilation.

Name four (4) major vessels attached to the heart, and explain where they receive blood from, and where they carry blood to 

Explain the term ‘normal sinus rhythm’

Complete the table on the heart valves below by briefly explaining the function of each and stating when each set of valves is closed. 

Fill in the blank boxes to complete TWO rows of your choice in the following table, which summarises the name, location and function of a variety of cells throughout the body. The first line is completed as an example of the level of detail required. Only the first TWO rows completed will be marked 

Name the personal protective equipment that should be worn when handling someone else’s urine, and explain why those items are needed.Protective equipment like gloves, gown and mask. This is to protect one from the spill overs and therefore reducing risk of exposure of the skin to infections.

Complete the table to compare how the following cells carry out the third line of defence:

• B-lymphocytes
• Cytotoxic T-lymphocytes

Some sections are completed for you to help guide your answers.

The following paragraph refers to muscle contraction. Fill in each of the blanks to complete the paragraph using terms from the list provided.  More terms than necessary are provided, and terms may be used more than once. (0.5 mark each; total 3 marks)

• The action potential spreads along the sarcolemma                       , until it reaches a T-tubule. The action potential continues down the T-tubule, where it triggers the release of           Ca²⁺        from the             sarcoplasmic reticulum                     . This exposes binding sites on     actin     .               Myosin  heads bind to the exposed sites on         actin      to form cross-bridges.

Describe the role of osteoblasts and osteoclasts in the regulation of blood calcium ion concentration.  You must include the role of the relevant hormones for full marks. (3 marks)

The action of osteoclasts is stimulated by Parathyroid hormone when the level of calcium in blood falls. This leads to calcium being transferred from bone to blood. Calcitonin on the other hand lowers the osteoclasts activity and thereby reducing the breakdown of bone.

Describe how the hypothalamus controls the release of hormones from the:

1. anterior lobe of pituitary gland
2. posterior lobe of the pituitary gland

In your answer, give specific examples and clearly name any hormones involved. (2 marks/lobe)

The anterior lobe will produce hormones upon getting the inhibiting or releasing hormones from the hypothalamus. For example, the release of Growth Hormone Releasing Hormone and Growth Hormone Inhibiting Hormone from hypothalamus controls the levels of Growth hormone release by anterior lobe.

The posterior lobe has nerve endings cells from the hypothalamus whereby the hypothalamus sends hormones straight to this lobe through this nerves and then they are released by pituitary gland. For example, during suckling by a baby, sensory receptors found in the nipple sends signals to hypothalamus and in turn oxytocin is secreted and released to bloodstream.

Duchenne muscular dystrophy (DMD) is recessive sex-linked disorder, which causes muscle degeneration and premature death. A couple is pregnant with a boy and neither has DMD. The father’s family has no history of DMD, but the mother is unsure of her genetic family history as she was adopted. The mother decides to take advantage of some of the new genomic screening tests and learns information about a large number of her genes. She finds that she is a carrier of the DMD-affected allele.

1. What is the mother’s genotype? Explain your reasoning. 

XdX. this is because the dominant allele will be seen but the individual will still be having recessive trait gene.

1. What is the father’s genotype? Explain your reasoning. Because he has no history of DMD in the family.

1. What is the likelihood of the male foetus having DMD? Use a Punnett square to explain your answer.

Mother’s genotype

X^d                                              X

e changes in volume and pressure inside the chest cavity during a normal, quiet exhalation. Explain why these changes are occurring, and the effect upon airflow.

The volume decreases and thus increasing the pressure in thoracic cavity. This is because the diaphragm relaxes and external inter coastal muscles contract and lungs and thoracic wall moves inward. Upon airflow the air moves out of the lungs until equal pressure inside and out is achieved.

Regarding quiet ventilation, which process is active — inhalation or exhalation? Briefly explain your answer.Inspiration is an active process. This is because it needs muscular contractions.

The graph below displays the oxygen dissociation curve and factors that affect the release of oxygen from haemoglobin (Hb). Explain how these factors will affect the release of oxygen into the blood supply of a hard-working skeletal muscle. 

When the temperature is increased, the affinity of haemoglobin for oxygen decreases hence reduce supply into the skeletal muscle blood supply. Lower temperature on the other hand will increase the affinity of haemoglobin for oxygen hence more supply. Higher pH and lower co2 increases the haemoglobin affinity for oxygen and this will increase the release of oxygen into the skeletal blood supply whereas lower pH and higher co2 leads to decrease oxygen release into the skeletal muscle since it lowers the affinity of haemoglobin for oxygen.

Choose ONE of the blood types below and answer the following questions. Only the FIRST completed column will be marked

1. State the type of antigens found on the surface of those red blood cells, and the type of antibodies found in the plasma of a person with the blood type shown. Type your answer in the table below
2. Could a person with your chosen blood type safely receive type AB blood via transfusion?  Explain your answer below. 

Blood group A cannot receive type AB blood since donor with blood type AB can only donate to recipients with blood type AB only.

Why is injury to the medulla oblongata usually fatal

Medulla oblongata functions to regulate heart rate, breathing and reflex actions. Therefore, injury may lead to abnormal regulation of the heart rate and breathing hence being fatal.

Complete the following table summarising the effects of autonomic innervation on target tissues. You must include both the effect upon the target tissue and a consequence of this stimulation in your answer.

The first row has been completed as an example.

The paragraph below relates to this graph, which describes changes in membrane potential over time.

1. Fill in each of the blanks to complete the paragraph using terms from the list provided. More words than necessary are provided, and terms may be used more than once.
2. during                   hyperpolarisation            , the ­      resting membrane potential       of the cell is 70 mV more negative than the               outside                 of the cell.  When a stimulus is applied, the membrane potential must reach        peak action potential                in order for an Action Potential to be fired.  At the start of an Action Potential, Na⁺ channels open and Na⁺ ions                            enters   the cell.  This phase is called       depolarisation                   . 

The        repolarisation                                    is the period of time in which the nerve membrane can start another action potential only if a much greater stimulus than usual is applied.

Referring to the graph above, at which numbered point do potassium gates begin to open

Antidiuretic hormone and aldosterone influence water and electrolyte balance of the body. The following table summarises the main characteristics of these hormones; your task is to fill in the empty cells in the table.

The following table describes the three elementary steps of urine formation. Complete the missing parts of the table.  

List two (2) differences between the external and internal urethral sphincters. The differences must relate to structure, function or innervation of these sphincters. (0.5 marks/difference; 1 mark total)

Internal urethral function to prevent t prevent reflux of seminal fluid during ejaculation sphincter is under involuntary control, consist of smooth muscle which is continuous with detrusor and parasympathetic impulse induce contractions and relaxation. While external urethral sphincter function to inhibit the release of urine, it consists of striated muscle, its innervated by pudental nerve, it’s under voluntary control

Explain how baroreceptors contribute to control blood pressure during a short period of widespread vasodilation.

When there is increase in blood pressure in the aorta or the carotid sinuses, the walls of these arteries stretch and stimulate increased activity within the baroreceptor which in turn decrease total peripheral resistance and decreases blood pressure.

Name four (4) major vessels attached to the heart, and explain where they receive blood from, and where they carry 

Explain the term ‘normal sinus rhythm’.Sinus rhythm refers to a normal heartbeat both with respect to the heart rate and rhythm.it is a cardiac rhythm where depolarization of the cardiac muscles begins at the sinus node.it has a characteristic of correctly oriented p waves on electrocardiogram.

References

Spencer, H. (2018). The Principles of Biology, Volume 1 (of 2). Litres.

Abercrombie, M., Hickman, C. J., & Johnson, M. L. (2017). A dictionary of biology. Routledge.